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[1] In an average adult, only a small amount (approximately 10% of a therapeutic paracetamol dose) of NAPQI is produced, which is inactivated by conjugation with glutathione (GSH)

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When excessive erythrocyte phagocytosis or ferritin degradation triggered by Mycobacterium tuberculosis infection leads to increased iron content [58], iron balance mechanism may be disrupted, resulting in cellular ferroptosis

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doi: 10.1021/acs.jmedchem.5b00669