doi:10.2147/ijwh.S165474
There were other secondary improvements as well, including a 39% reduction in serum alanine transaminase (ALT), and a 30% drop in aspartate transaminase (AST), suggesting overall improvement in liver function
Rossing P, Filippatos G, Agarwal R, Anker SD, Pitt B, Ruilope LM, Chan JCN, Kooy A, McCafferty K, Schernthaner G, et al
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After talking to hundreds of patients with obesity over the years and to clinicians and researchers who study the disease, let me assure you: Reality looks a lot less like free will. Weight gain and weight loss are a complex orchestra of hormones that tell the body when were hungry and when were full
After 72 weeks, participants on Zepbound lost an average of 20.2% of their body weight (averaging 50 pounds), compared to 13.7% (around 33 pounds) for those on the 2.4 mg dose of Wegovy (later studies of the 7.2 mg dose of Wegovy have showed 18.7% weight loss)