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Proline is exceptional in that it has an R group that folds back and covalently bonds to the backbone of the amino acid, creating a more rigid element in a protein chain that reduces free movement of the polypeptide chain

The treatment is regarded as relatively safe, but like any medicine, has potential side effects: Diarrhoea Dizziness Headache Hot flush Nausea Skin reactions Urine discolouration If you are allergic to cobalt please notify your clinician (1-3% of the population have this allergy)

Those with blood pressure concerns should monitor accordingly