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Select probiotics wisely: Lactobacillus probiotics can produce histamine, so seek out other strains, including bifidobacteria, spore-based probiotics, and yeast-based saccharomyces boulardii

Growth factors like nerve growth factor (NGF), Stem cell factor (SCF), and hepatocyte growth factor (HGF) support melanocytes, while transforming growth factor- (TGF-) and glucocorticoid receptor (GR) inhibit them