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Grading of recommendations, assessments, development, and evaluation (GRADE) criteria 19 were used to establish the evidence level for each clinical recommendation

10.2337/diabetes.54.12.3458 9 BoseS

While complete Phase 3 data is pending, the trial design incorporates the escalation framework validated in Phase 2 starting at lower doses and escalating over defined intervals to target maintenance doses

The focus on UPFs reflects growing global concern regarding their widespread consumption and potential implications for health and wellbeing

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