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Because the compound lacks regulatory approval, any product marketed for human use is being sold through unofficial channels that do not meet pharmaceutical manufacturing standards, raising documented concerns about purity, composition, and contamination

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A 2024 review in Cartilage identified AOD-9604 among key peptides recognized for benefits to bone and joint health, noting its capacity for chondrogenic induction and cartilage regeneration in osteoarthritis models

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Injection-specific risks include injection site reactions, infection, and improper reconstitution errors