People with type 2 diabetes often have high blood sugar
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Glucagon-like peptide-1 receptor agonists are similar to the GLP-1 hormone, which is secreted in the gastrointestinal tract in response to eating
Mechanistically, combining these peptides may amplify insulin secretion suppression and gastric emptying delay, creating cumulative gastrointestinal effects
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Breakthroughs in multi-omics technologies have confirmed that gut microbiota and their metabolites play a crucial role in regulating the pathological progression of IBD ( This review focuses on describing local intestinal iron metabolism, the regulation of iron homeostasis, and host-microbiota interactions based on current research findings, while also elucidating the underlying molecular mechanism of metabolite-modulated ferroptosis plasticity