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Nuclear IGF-IR regulates gene expression While IGF-IR is usually localized at the plasma membrane in normal cells, it often translocates into the cytoplasm and nucleus in cancer cells even though it does not have the nuclear localization signal [78,79,80]

For the purposes of this article, we will only touch on the peptide hormones, examples are insulin, GLP-1, and oxytocin

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A key process that connects metabolic issues in the body to brain-related problems is the movement of A from the bloodstream into the central nervous system (CNS)