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Although oxidative stress may not be the only cause of cell derangement and of disease, an ever-increasing number of disease conditions at several organs and systems, such as cancer, cardiovascular, neurodegenerative and endocrine diseases, are linked to this altered state

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The 50 mg vial is reconstituted with 2 mL of bacteriostatic water to achieve a 25 mg/mL concentration (0.25 mg per unit)

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On the contrary, multidrug resistance-associated proteins MRP1, MPR4, and MPR5 are not only involved in the uptake of antimalarial drugs but also in the efflux of some metabolites (e.g., oxidized glutathione conjugates and cyclic nucleotides) (Figure 1)