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Cardiovascular Outcomes with Orally Administered Semaglutide PIONEER 6 (NCT02692716) was an event-driven CVOT designed to confirm that treatment with orally administered semaglutide does not result in an unacceptable increase in CV risk compared with placebo

They mimic the effects of glucagon-like peptide-1 (GLP-1), a hormone involved in regulating appetite

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