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The typical ratio is that about 20-30% of weight lost is lean mass

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Current insight into the cardiovascular biology of GIP is limited, and findings in preclinical and clinical studies point in different directions, ranging from potentially cardioprotective effects to heightened vascular inflammation and artherogenesis 24,25

Lau T, Cook J, Archid R, Stengel A, Zipfel S, Mack I

Conclusion: Our results demonstrate ccfDNA release during adipogenesis and lipid accumulation