Effect of long-acting liraglutide QD on HR A 24-h time-averaged increase in mean placebo- and baseline-adjusted HR of 78 bpm was reported following liraglutide 1.2 and 1.8 mg QD (titrated in 0.6-mg weekly steps) using serial ECG monitoring at the end of the second and third weeks (after the seventh and final dose) of liraglutide (N = 51)
Cell Mol Life Sci : CMLS 73(4):737755 Ahmed H, Leyrolle Q, Koistinen V, Krkkinen O, Lay S, Delzenne N et al (2022) Microbiota-derived metabolites as drivers of gutbrain communication
While unpleasant, these physical symptoms can also indirectly deter substance use, because the user may develop a physical aversion to drinking alcohol (since it makes them nauseous)
It may take trial and error (and patience during titration) to see what works for your body
Supplementary information Supplementary materials, Supplementary Figs
Typical weekly self-injection doses in hypogonadal men run 50 to 200 mg/week, titrated to a trough testosterone target of 400 to 700 ng/dL per most clinician protocols