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(Source: PMC / JCI, 2026) Mental health monitoring: If you experience new or worsening depression, anxiety, or thoughts of self-harm while on or after stopping a GLP-1, contact your clinician promptly

A randomized controlled trial conducted by Dixon et al.57 showed that the dual administration of prebiotics and metformin produced favorable changes in the microbiota but did not reduce the gastrointestinal adverse effects

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Avoid greasy or spicy foods: These may worsen symptoms

To achieve the best outcomes, this may involve a combination of medicine, diet, exercise, and other lifestyle changes

Many patients find the act of manual entry increases awareness and engagement