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Abstract With the huge negative impact of neurological disorders on patients life and society resources, the discovery of neuroprotective agents is critical and cost-effective

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People are very familiar with that in terms of when you take an antihistamine and you may get drowsy

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Activating GLP-1R inhibits PFKFB3-driven glycolysis and histone lactylation in TGF-1 + IL-1-stimulated fibroblasts Our results demonstrated that TGF-1 + IL-1 augmented PFKFB3-driven glycolysis, lactate production and histone lactylation in fibroblasts in vitro (Fig