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doi:10.1016/j.ghir.2014.12.005

Regulation of Sirt1 on energy metabolism and immune response in rheumatoid arthritis

If anything becomes worse rather than better after 48 to 72 hours, call the clinician who gave you the shot

Contraindications that apply regardless of dose: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Prior serious hypersensitivity to semaglutide Pregnancy or breastfeeding Active pancreatitis or a history of severe pancreatitis Severe gastroparesis Adverse events that can occur at any dose: nausea, vomiting, diarrhea, constipation, abdominal pain, gallbladder disease, acute kidney injury from dehydration, injection-site reactions, and rare cases of pancreatitis

Treatment should be stopped if these criteria are not met