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Sikiric et al., 2020b), additionally acting as membrane stabilizer (Park et al., 2020), with particular reference to ulcerative colitis (Sikiric et al., 2011)

Shaking creates foam, introduces air bubbles, and causes physical stress that degrades the peptide through a process called denaturation

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In the CY 2011 PFS final rule (75 FR 73256), we acknowledged that we typically update the GPCI cost share weights concurrently with the most recent MEI rebasing and revision, but in consideration of the commenters' concerns in response to the proposed rule, we did not use the revised cost share weights for the CY 2011 GPCIs and instead finalized the implementation of the rebased and revised MEI cost share weights through subsequent rulemaking