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Randomized controlled trials will eventually answer the questions that pilot studies and mechanistic evidence can only suggest

Retatrutide is a novel triple receptor agonist targeting GLP-1, GIP, and glucagon receptors under clinical evaluation for obesity and type 2 diabetes

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Clinical Considerations Disease-associated maternal and/or embryofetal risk Appropriate weight gain based on pre-pregnancy weight is currently recommended for all pregnant patients, including those who already have overweight or obesity, because of the obligatory weight gain that occurs in maternal tissues during pregnancy

10.1007/s11695-009-0014-5 13 CalaraF.TaylorK.HanJ.ZabalaE.CarrE

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