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If nausea or other GI side effects persist beyond 4-6 weeks despite dose stabilization, provider guidance should address whether to continue, adjust the formulation, or transition to an alternative

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People who expect immediate dramatic results are more likely to feel disappointed and conclude the medication is not working, even when early physiological changes are occurring

[9] This weight reduction can further improve insulin sensitivity and restore menstrual regularity in many women with PCOS

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