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Somatotroph cells receive two positive signals simultaneously and the physiological brake is released

The second piece of evidence was obtained with mice in which the K ATP channels were disrupted

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To observe the central behaviour of the system only, the median substrate concentrations with their interquartile ranges were taken from each simulation run

Moreover, Trx and Grx preserve the reduced state of the cell by reducing oxidized thionine residues in actin to protect the morphology of the cytoskeleton (Meyer et al., 2012)