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The ATP-binding cassette-containing (ABC) family of proteins includes active drug efflux transporters like P-glycoprotein (P-gp), multidrug resistance-associated proteins (MRPs), and breast cancer-resistant protein (BCRP), which can exert a significant impact on placental transfer [85,86]

Weight loss of 5% to 10% of total body weight has been shown to improve both metabolic and reproductive aspects of PCOS

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These medications are not FDA-approved, and no claims are made regarding their safety, efficacy, or quality