10.1046/j.1365-201X.2001.00820.x
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Why Some Peptides Should Never Be Used Long-Term: The Case of Angiogenesis Peptides Angiogenesis peptides stimulate the growth of new blood vessels powerful for tissue repair, wound healing, nerve regeneration, and circulation
doi: 10.3390/ijms231810902 27 YangYJiangXXuHChenGWangSZhangHet al
These new findings encourage a novel working hypothesis for further research, that a chemical-modification mechanism enables transformation of HGF through interaction or reaction with LASSS under physiological conditions, resulting in the retention of HGFs biological activity after exposure to peroxynitrite, at least until an enhanced form of HGF undergoes metabolic turnover in vivo