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The primary outcome of this study was the first diagnosis of CRC within 15 years from the initial treatment of GLP-1RAs or non-GLP-1RA diabetes medications (insulin, metformin, alpha-glucosidase inhibitors, dipeptidyl-peptidase-4 inhibitors (DPP-4i), sodium-glucose cotransporter-2 inhibitors (SGLT2i), sulfonylureas (SU), and thiazolidinediones (TZD))

The details of such reactions are extensively reviewed in previous publications [77, 79]

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In vitro, eosinophils were shown to exert antiparasitic activity through the release of cytotoxic granules, reactive oxygen species or nitric oxide, the formation of eosinophil extracellular DNA traps or by promoting macrophage activation (da Silva Marques et al, 2021

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