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Since the patient is the sole source of the stem cells, there is no requirement to find a matching donor, negating the possibility of GVHD [149]

Cytokines and chemokines including TNF-, IL-6, and IL-1 cross BBB and induce neuroinflammation directly, and also by activating inflammatory, glial, and neuronal cells in the brain (Banks et al., 2016)

There are 1.7 million incidents of traumatic brain injury (TBI) in the USA alone, each year

Summary Semaglutide reduces appetite by activating GLP-1 receptors in brain satiety centers, a mechanism that, in trials, has been associated with an average weight loss of 14.9% over 68 weeks

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