Simultaneously, a consortium of additional organelles-including the endoplasmic reticulum, peroxisomes, Golgi apparatus, and lysosomes-advances this cell death pathway through their involvement in lipid remodeling, antioxidant balance, and the autophagic turnover of ferritin ( in vivo models ( GPX4, in conjunction with its active-site selenocysteine (Sec46), contains seven other cysteines (Cys2, Cys10, Cys37, Cys66, Cys75, Cys107, and Cys148), all potentially reactive with electrophiles
& Stephanopoulos, G
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After reconstitution, aliquot and store at 20 C to preserve structural stability
doi:10.1200/JCO-24-01349 Ahn MJ, Tanaka K, Paz-Ares L, et al
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