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Under hypoxic conditions, L-2-hydroxyglutarate (L-2-HG) was proven to be generated by lactate dehydrogenase A (LDHA) and malate dehydrogenase (MDH) 88,89

10.1021/acs.jpcb.5b02891 75 LiJ.YuX.JiangY.HeS.ZhangY.LuoY.et al (2021)

Tumor hypoxia unveiled: insights into microenvironment, detection tools and emerging therapies

At the heart of the hangover experience are three key processes: the way your body metabolizes alcohol, the oxidative stress generated during this process, and the depletion of vital antioxidants such as glutathione

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