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Back to Journals Journal of Pain Research Volume 12 Acetyl-L-carnitine in painful peripheral neuropathy: a systematic review Authors Di Stefano G, Di Lionardo A, Galosi E , Truini A, Cruccu G Received 9 October 2018 Accepted for publication 28 January 2019 Published 26 April 2019 Volume 2019:12 Pages 13411351 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor E Alfonso Romero-Sandoval Giulia Di Stefano, Andrea Di Lionardo, Eleonora Galosi, Andrea Truini, Giorgio Cruccu Department of Human Neuroscience, Sapienza University, Rome, Italy Abstract: Acetyl-L-carnitine (ALC) has shown a neuroprotective effect in patients with peripheral neuropathies of different etiologies

L-carnitine supplement administered orally or via IV can improve symptoms of heart failure and congestive heart failure (fluid buildup in the body)

Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice

Clinical laboratory tests Hormonal and biochemical assessments were carried out for all patients participating in the study in the Royan Institute laboratory