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CHE often presents with nonspecific symptoms, and differentiation from other conditions can be challenging, resulting in uncertainty regarding treatment indication in some cases [121]

Origin and turnover of mitochondrial glutathione

This selectivity suggests GHK-Cu acts as a tissue remodeling coordinator rather than a blunt inhibitor, preserving newly deposited matrix while facilitating cellular access to the wound site

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Examples of a neutral polymer include but are not limited to povidone, poloxamer, and HMPC