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, gastrointestinal tract, muscle, nerve, brain lesions healing)) (5-7, 9), and cytokine and growth factor generation and early extracellular matrix (collagen) formation (44)

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Under normal conditions, Nrf2 is anchored in the cell cytoplasm by a repressor protein called Keap1

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That can irritate joints and discs, which may further aggravate nerve pathways