Jalewa J, Sharma M, Gengler S, Hlscher C
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Some oral GLP-1 medications have shown strong clinical trial results, but results vary by medication, dose, adherence, side effects, and patient factors
Both semaglutide and liraglutide were shown to significantly increase weight loss in this patient population due to slower gastric emptying time, increased satiety, decreased hunger and food cravings, as well as alteration of the food reward pathway
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Nonetheless, in patients at high risk of sarcopenia, tailored management including nutritional optimization and concurrent resistance training should be considered to mitigate potential adverse consequences during pharmacologically induced weight loss [20]