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Anyone with these conditions should obtain explicit medical clearance before receiving a B12 injection

B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month

After the deficiency is fixed, injections might be needed only once a month

With your thumb and 3rd finger holding the middle of the syringe (similar to holding a pencil or pen but with different fingers) and your index finger on the plunger of the syringe, quickly insert the needle AT A 10-30 DEGREE ANGLE (this way it is impossible to go too deep) until it stops at the hub of the needle/syringe

High-dose oral therapy (10002000 micrograms daily) can be effective even in pernicious anaemia, as approximately 1% of B12 is absorbed through passive diffusion independent of intrinsic factor