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Cells were pre-plated for 1 h to enrich cardiomyocytes, seeded on laminin-coated dishes, and maintained in DMEM/F12 supplemented with 10% foetal bovine serum (FBS) and 1% penicillin/streptomycin

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Whilst blood in stool is not a recognised adverse reaction in the MHRA-approved Summary of Product Characteristics, patients may experience gastrointestinal side effectssuch as constipationthat can indirectly contribute to rectal bleeding

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