he also seems depressed and is not eating well
According to the NIH Office of Dietary Supplements, functional B12 deficiency is most commonly seen in patients with one or more of the following: Age over 50 stomach acid production declines with age, and stomach acid is required to free B12 from food PPI or H2 blocker use reflux medications suppress the acid needed for B12 absorption Metformin use, which interferes with B12 absorption directly Vegan or vegetarian diets B12 is found almost exclusively in animal products Gut conditions including celiac, IBS, SIBO, and Crohns MTHFR mutations that affect how B12 is metabolized once absorbed Heavy alcohol use The symptoms of low B12 are easy to dismiss: fatigue, brain fog, low mood, tingling in the hands or feet, weakness, and shortness of breath on mild exertion
As mentioned, a small case series (not a rigorous trial) found that people with knee osteoarthritis or chronic tendon injuries reported less pain and better function after BPC-157 injections
57% had an ABCD2 score 30 cohort was 32+/-15 min
Potential users should be aware that while preclinical safety appears excellent, the absence of extensive human clinical trials means unknown risks may exist
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