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The lack of long-term natural history studies on pediatric MASLD has created a significant gap in understanding the disease's progression over time

occasional mild injection-site reactions may occur with subcutaneous administration

If a family history of first degree relatives is made, that would qualify as evidence of criteria II, but in the absence of such, as can occur in patients who develop this disease de novo, or who do not know their family history well, have a syndrome complex of diffuse pain throughout the body for more than three months or at least two joints are required

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Endocrinol., Metab