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The only human data available comes from a 2025 pilot study by Lee and Burgess, published in Alternative Therapies in Health and Medicine

Treatment should be discontinued immediately if these signs occur and a medical professional should be consulted

According to Derek, Adherence is the number one killer of people not getting lean. To improve that, he focused on meals and supplements that crushed appetite, timed food intake to reduce cravings, and used smart food swaps to stretch calories