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2A -adrenergic receptors were labeled with HaloTag, and either G i1 or -arrestin2 were labeled with the highly-sensitive nanoluciferase (NanoLuc) as the nanoBRET pair

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Bioconjug Chem (2023) 34(7):132735

As in the previous figure, the bold line indicates serially observed change in the diabetics and the dotted line shows is a projection that assumes that if diabetics were to continue on the therapy for longer time period the asymptotic values of HOMA2-%B may lie close to the non-diabetic numbers

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10.1016/0006-2952(93)90085-B Biochem