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Weeks 5-10: Reduce intensity by 30 to 50 percent

Insulin as a physiological modulator of glucagon secretion

Joint pain during tirzepatide treatment may result from rapid weight loss altering biomechanics and joint loading, increased physical activity unmasking pre-existing joint issues, or underlying conditions like osteoarthritis that are common in patients with obesity and type 2 diabetes

While the Microdose Program uses a lower dose of the medication, it can still get you good results when paired with their online coaching platform

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These results align with the findings of Wang et al., 28 who reported a reduced incidence of liver cancer among individuals treated with GLP-1 receptor agonists