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Primarily stored in the liver , it also ensures important detoxification functions (18)

Semaglutide versus sitagliptin: in one set of analyses, we compared initiators of semaglutide with initiators of sitagliptin in patients at elevated cardiovascular risk with type 2 diabetes and obesity

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Moreover, liraglutide trials in patients with HFrEF provided no clinical benefit, underscoring that the efficacy of incretin receptor agonism does not uniformly extend across heart-failure phenotypes and that remodelling mechanisms may differ by disease context [47]