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US20210186943A1 - Otic formulations for drug-induced ototoxicity - Google Patents Otic formulations for drug-induced ototoxicity Download PDF Info Publication number US20210186943A1 US20210186943A1 US17/050,421 US201917050421A US2021186943A1 US 20210186943 A1 US20210186943 A1 US 20210186943A1 US 201917050421 A US201917050421 A US 201917050421A US 2021186943 A1 US2021186943 A1 US 2021186943A1 Authority US United States Prior art keywords formulation otic composition therapeutic agent agent Prior art date Legal status (The legal status is an assumption and is not a legal conclusion
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By week 8, most patients report feeling normal energy levels and food tolerance returning, though appetite suppression remains strong
However, animal studies indicate that they could be harmful to the developing fetus
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