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Food scarcity, neuroadaptations, and the pathogenic potential of dieting in an unnatural ecology: binge eating and drug abuse

Keywords: N-acetylcysteine, Fatty liver disease, Hepatic steatosis, Metabolic dysfunction, Metabolic profile, Clinical trial Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as nonalcoholic fatty liver disease (NAFLD), is defined as fat accumulation in more than 5% of liver cells when other risk factors for fat accumulation, such as alcohol or drugs, have been ruled out

The hyperexcitable state in epilepsy can be conceptualized as an imbalance in the normal processes of synaptic strengthening (LTP) and weakening (long-term depression, LTD), leading to a pathological enhancement of synaptic efficacy (Kopec et al., 2007

Combination therapy with once-weekly glucagon like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes: a case series

IDF Diabetes Atlas, 9th edn

The resulting influx of Ca2+ causes vesicular exocytosis of GLP-1-containing vesicles