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Endocrinology 139:41084114 Li G, Hidaka H, Wollheim CB (1992) Inhibition of voltage-gated Ca 2+ channels and insulin secretion in HIT cells by Ca 2+ /calmodulindependent protein kinase inhibitor KN62: comparison with antagonists of calmodulin and L-type Ca 2+ channels

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Too many hoops to jump through, outdated warnings based on fears that never panned out, and a treatment that's technically classified alongside ketamine as a controlled substance

De Simone R, Ajmone-Cat MA, Carnevale D, Minghetti L (2005) Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures

Placebo-treated patients switched to the active drug at 24 weeks and continued until week 52

However, LXR agonist GW3965 increased the expression of LXR target gene ABCA1 without affecting RSL3 induced ferroptosis (Supplementary Fig