The most detrimental clinical presentation is fulminant liver failure, where patients without a history of liver disease present with hepatic encephalopathy and coagulopathy preceding jaundice
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Evaluation of the effects of curcumin in patients with metabolic syndrome
435 HSPs and inflammasome regulation in autoimmune diseases Inflammasomes are multiprotein complexes that play a central role in innate immunity by regulating the production of pro-inflammatory cytokines, such as interleukin-1 (IL-1) and IL-18
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114,115 Mitochondrial NADH supplies NADH dehydrogenase (complex I) with electrons, which along with the electrons obtained from FADH 2 via complex II drive the mitochondrial ETC to generate a proton (H + ) gradient across the IMM for the production of ATP