Ingelheim, Germany Boehringer Ingelheim today announces the start of a Phase II clinical trial evaluating its investigational triple GLP-1/GIP/NPY2 receptor agonist, BI 3034701, in patients with obesity and overweight
The weight gain from the insulin and the weight loss from the GLP-1 essentially cancel each other out
Anti-IGF-1 receptor (IGF-1R) monoclonal antibodies (mAbs) were developed for clinical use in treating advanced stage cancers 22,23,24 , including Ganitumab, which remains under investigation as a combination therapy in clinical trials targeting Rhabdomyosarcoma (NCT03041701) and Ewing Sarcoma (NCT02306161), for which it recently received orphan drug status
It functions by binding to CD2 molecules on the surface of activated T cells, thereby inhibiting the costimulation of T cells by APC
Balmer ML, Siegrist K, Zimmermann A, Dufour J
In 2026, they offer free shipping on orders over a certain threshold (usually $200), which is easily met in most laboratory settings