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Bringing a new drug to the market is a long, expensive process, and one that excited consumers are easily bypassing

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However, it has been found that up to 20% of initially hypothyroid individuals will later recover and have normal thyroid function if challenged by replacement hormone withdrawal

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Beyond weight loss, GLP-1 medications improve insulin signaling, reduce systemic and neuroinflammation, enhance mitochondrial efficiency, and exert direct effects on neurons and glial cells to maintain neurological cell health [2]

Adding this anabolic support to a retatrutide-driven caloric deficit could theoretically shift the composition of weight loss toward greater fat loss and less muscle loss