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The global trial is a Phase 1b/2a trial investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of the doses of UBT251 for up to 28 weeks in about 330 people who are overweight or obese

2021;320:E87485

Electrophysiological recordings revealed that exendin-4 increases the frequency of spontaneous excitatory postsynaptic currents (sEPSCs) of VTA dopaminergic neurons suggesting the possible presynaptic modulation of GLP-1R on glutamatergic terminals

It can improve aging, prevent chromosome fusion, and reduce cellular senescence

Quick Answer: Brain fog is not listed as an official adverse reaction to Wegovy in UK prescribing information, though some individuals report cognitive symptoms that may relate to dietary changes, dehydration, or metabolic factors rather than the medication itself

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