Acronyms CrCl - Creatinine clearance GLP-1 - Glucagon-Like Peptide-1 P - Drugs with pediatric dosing Dulaglutide Trulicity Trulicity Dosage forms Single-dose pen 0.75 mg/0.5 ml 1.5 mg/0.5 ml 3 mg/0.5 ml 4.5 mg/0.5 ml Comes in carton with 4 pens Dosing Type 2 diabetes Starting: 0.75 mg once weekly Maintenance: 0.75 - 4.5 mg once weekly Max: 4.5 mg once weekly Increase to next higher dose if needed at intervals of 4 weeks May administer without regard to food If a dose is missed, administer ASAP if there are at least 3 days until the next scheduled dose If less than 3 days remain before the next scheduled dose, skip the missed dose and administer the next dose on the regularly scheduled day In each case, patients can then resume their regular once weekly dosing schedule The day of weekly administration can be changed if necessary as long as the last dose was administered 3 or more days before Kidney disease No dose adjustment is recommended in patients with renal impairment including end-stage renal disease Gastrointestinal side effects may be worse in patients with kidney disease Liver disease In a study of patients with varying degrees of liver disease, no clinically relevant change in dulaglutide pharmacokinetics was observed
4 Thirty-seven percent of Gen Alpha (born 2010 2025) receive mental health care for anxiety, depression, attention deficit hyperactivity disorder (ADHD), and/or autism
We modeled an optimistic scenario using the best possible weight loss outcomes and long-term risk reductions, said first author Jennifer Hwang, DO, a primary care physician at UChicago Medicine
The peptide stack calculator helps with planning dosing across multiple compounds
If progress feels slow or nonexistent, it may be worth discussing dose adjustments or other strategies with your Hers provider
Many people hear about new drugs on social media and assume theyre available
