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Its effects are systemic meaning they influence the entire body and tend to build gradually over weeks to months

Nayak NC, Chitale AR

Translational percentages (concordance rates) of results exhibit a wide range from 0100% with no predictable factors for translational success or failure in humans (309), and even multiple experiments fail to significantly contribute to improving the reproducibility of animal testing, accounting for 41%72% of the observed total variance (310, 311)

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[DOI] [PubMed] [Google Scholar] 56.Padmanabha Das KM, Wechselberger L, Liziczai M, De la Rosa Rodriguez M, Grabner GF, Heier C, et al

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