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A randomized controlled trial is currently underway evaluating prophylactic metformin for patients starting clozapine (Siskind D et al, BMJ Open 2018;8(3):e021000)

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Understanding why B12 may help requires understanding why GLP-1 medications cause nausea in the first place

The European Medicines Agency's assessment report also acknowledges headache among the common adverse reactions associated with semaglutide treatment for weight management

Understanding genetic context may reduce trial-and-error medication cycling by highlighting mechanisms most aligned with metabolic phenotype