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2.3 Dose Modifications for Drug Interactions Dosage adjustments are recommended in patients taking concomitant strong CYP3A4 or CYP2C8 inhibitors or strong CYP3A4 or CYP2C8 inducers [see Drug Interactions (7.1), Clinical Pharmacology (12.3)]
A separate 2025 cohort study from Weill Cornell found greater annualized hip bone loss in GLP-1RA users without diabetes compared to matched non-users
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Common dosing ranges In sports medicine and integrative settings, the dosage ranges: Subcutaneous injections : Approximately 200 to 500 mcg per day