Gallstone disease and rapid weight loss create a compounding risk profile
GLP-1(7-36) cAMP PKA EPAC
(Exercise should always be cleared with plastic surgeons following procedures.) Several of the surgeons I spoke to include the peptide-rich Alastin Reform & Repair Complex in their pre-op protocols, having patients apply the serum to treatment areas, twice daily, starting at least six weeks before surgery
However, recent insights suggest that the gut and brain GLP-1 systems operate largely independently with mRNA transcripts for proglucagon (GCG), the precursor peptide for GLP-1, being abundant in the brainstem, particularly within the nucleus tractus solitarius (NTS
For oral semaglutide (Rybelsus), the typical starting dose is 3 mg once daily for the first month, increasing to 7 mg once daily after 30 days if tolerated
McCrimmon RJ, Catarig AM, Frias JP, Lausvig NL, le Roux CW, Thielke D, et al