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Now I need to get into the mechanism of why this happens

The priming signal involves the upregulation of NLRP3 expression and the synthesis of proinflammatory cytokines such as TNF- and IL-1, typically mediated by nuclear factor kappa B activation in response to inflammatory stimuli

The authors of this review point to several studies indicating that some short-chain fatty acids (SFCAs) produced by gut bacteria increase the production and release of GLP-1 into the bloodstream

Nevertheless, recent investigations have highlighted several shortcomings

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